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Year : 2012  |  Volume : 1  |  Issue : 2  |  Page : 104-108

Similar caries pattern in monozygotic twins: Role of nature and/or nurture

1 Department of Pedodontics, K.M. Shah Dental College, Sumandeep Vidyapeth, Vadodara, Gujarat, India
2 Department of Periodontics, K.M. Shah Dental College, Sumandeep Vidyapeth, Vadodara, Gujarat, India

Correspondence Address:
Anshula Deshpande
Department of Pedodontics,K. M. Shah Dental College, Sumandeep Vidyapeth, Vadodara - 391 760,Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-9626.103397

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The present article attempts to relook at the role of genetics in the caries pattern in pediatric patients. Genetics exerts a major influence on initiation and progression of caries. Several investigators have studied the genetic aspects in humans using both twin studies and family pedigree approaches. The recent advances in molecular biology and the outcomes of the Human Genome Project can help to have innovative approaches to understand the etiology of this complex disease. A pair of 5-year-old monozygotic twin brothers was referred by the Pediatrician for multiple caries. Both the brothers were reared apart but presented with similar dental caries traits. Comprehensive oral health care with a preventive and therapeutic procedure was provided. Periodic recall visits were scheduled after every 6 months. By studying dental diseases in the twins reared apart, the element of environmental influence is eliminated while retaining the advantage of similar genotype in monozygotic twins. This report of monozygotic twins imparts light on the significant contribution of genetic factors on caries susceptibility.

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