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ORIGINAL ARTICLE
Year : 2014  |  Volume : 3  |  Issue : 1  |  Page : 22-28

Insights into functional tea infused-chitosan hydrogels as potential bio-active restorative materials


1 School of Dentistry and Oral Health, Research and Development, VTPCHEM PTY LTD, Griffith University, Southport QLD 4215, Melbourne, Victoria 3163, Australia
2 School of Material Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
3 Faculty of Dentistry, Oral and Dental Research Institute, University of the Western Cape, Private Bag X1, Tygerberg 7505, Cape Town, South Africa

Correspondence Address:
Tamara V Perchyonok
School of Dentistry and Oral Health, Griffith University, Southport QLD 4215
Australia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-9626.126205

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Introduction: We described novel chitosan hydrogels (chitosan-H) containing tea infusions (green, red and black) as functional additive prototypes with special focus on the design and functionality of dual action composite restorative materials. Their intended uses include remineralizing bases/liners, therapeutically active restorative materials and/or functional additives as well as functional prototype of the drug delivery system. Materials and Methods: The above mentioned hydrogels were prepared by dispersion of the corresponding component in glycerol and acetic acid with the addition of chitosan gelling agent. The surface morphology scanning electron microscope (SEM), release behavior (physiological pH as well as acidic conditions), stability of the hydrogels as well as antioxidant capacity of the tea infused hydrogels was evaluated. Results: It was found that all the anti-oxidant chitosan-H hydrogels treated dentine gave significantly (P < 0.05; Non-parametric ANOVA test) higher shear bond strength values than dentine treated or not treated with phosphoric acid. Overall, there was a small relapse in the shear bond strength after 6 months. The SEM is employed to observe the surface of the newly made functional restorative materials. The anti-oxidant capacity of various black, red and green tea infusions was investigated and demonstrated increased antioxidant stability of the newly prepared material stability. Conclusion: We have developed and evaluated several functional chitosan hydrogels with several targets as therapeutic restorative materials, the added benefits of their unique functionality involve increased dentin adhesive bond strengths (after 24 h and after 6 month), concept of using functional materials as carriers for pro-drugs as well as display certain degree of defense mechanism for a free radical damage.


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